More than 400 sites in the Western Victoria Primary Health Network (PHN) catchment are readying themselves for the inaugural go-live of the state's SafeScript real-time prescription monitoring system, which will begin tomorrow.

The $29.5 million SafeScript program, the technology for which has been built by Fred IT using its eRx Script Exchange system in partnership with MediSecure, will be rolled out to the rest of the state next year and will be mandatory for doctors, pharmacists and nurse practitioners to use from April 2020.